John Mandrola
Person on 3 sites
Cardiac electrophysiologist in Louisville, Kentucky. Co-writes the Sensible Medicine newsletter, where he reviews cardiology and other clinical trials, and…
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4 facts on wiqqi (opens wiqqi.app)
Who people, organisations and podcasts are, and how they connect, with sources.
Updated 2026-11-01 -
3 channels on ppll (opens ppll.app)
Where public figures publish, and what they are on record saying.
Updated 2026-10-19 -
15 beliefs on korrents (opens korrents.com)
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The NHS-Galleri trial did not show a reduction in late-stage cancers. (opens korrents.com)
“Yet there was no reduction in late-stage cancers, the primary endpoint.”
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The Grail multicancer blood test has poor sensitivity and test characteristics. (opens korrents.com)
“But it had a terrible sensitivity of only 30%, meaning it missed a lot of cancers.”
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The Grail test results are not reassuring because a positive test is often a false positive and a negative test does little to reduce baseline risk. (opens korrents.com)
“A positive test leads to as many false positives as true positives, and a negative test is not at all reassuring.”
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The NHS-Galleri trial did not show a reduction in late-stage cancers. (opens korrents.com)